Kotono Mitsuishi is a prolific Japanese voice actress whose career has indelibly shaped the landscape of anime for decades. Her iconic vocal performances have graced some of the most influential animated works, making her a household name among fans and a key figure for collectors of Japanese animation. Her ability to infuse characters with a unique blend of vulnerability, strength, and charm has made her roles instantly recognizable and deeply impactful across various genres. For physical media enthusiasts, Mitsuishi's name is synonymous with collecting cornerstones. Her portrayal of Usagi Tsukino in *Sailor Moon* (debuting 1992) represents a foundational anime, with numerous home video releases across VHS, DVD, and Blu-ray being highly sought-after. However, it's her dynamic performance as Misato Katsuragi in *Neon Genesis Evangelion* and its cinematic conclusion, *Neon Genesis Evangelion: The End of Evangelion* (1997), that truly elevates her to collector royalty. These releases, especially the numerous limited edition Blu-rays and 4K sets, are consistently on watchlists for their historical significance, stunning animation, and Mitsuishi's unforgettable voice work. Fans also prize her later roles like Murrue Ramius in *Mobile Suit Gundam SEED* (2002), further cementing her legacy in anime's golden age of physical media.